Just a couple of points I'd like clarification on (apologies for skimming down your post). Hoping I don't cause a rift at all, just want some more depth to your thoughts.
What are the alternatives to clinical trials? Ultimately, and this may come across callous, clinical trials are designed (regardless of who has generated the directive/guidelines) to give a full understanding of a drug's effect before reaching the intended populous. Unfortunately, there are going to be cases of drugs which work well on 'paper' but exhibit complications that have been otherwise unforeseen, even with the development of computational modelling. Is this an issue that spans only EU-wide? Yes, things are slow to change but it's still the case of slow-to-change in 'independent' countries such as USA where law cannot keep up with technology.
How have procurement laws turned out to be destructive? I can understand that there's a time and cost implication as per your quote, but how might this differ to being outside the EU and still (potentially) relying on EU members for procurement? Could there be an added time/cost implication for trading with a country outside of 'the' trade agreement?
Would a constant chop/change be beneficial? I do appreciate the democratic approach, that we can vote in the majority verdict, but would matters slow down if we're ending up becoming bored of a government (or their front-man/woman) on a 4-yearly basis and subsequently voting in an opposing viewpoint? If we're completely reliant on this, might it muddy waters for plans going ahead? I guess having an 'unelected' group can help rule out anomalous views?